RGS4 Antibody (Center) [APR32611G]

RGS4 Antibody (Center) [APR32611G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This RGS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the Central region of human RGS4.

Cellular Localisation: N/A

Molecular Weight: 23256

Clone: Polyclonal

Gene Name: RGS4

Gene ID: 5999

Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G (z) -alpha is inhibited by phosphorylation of the G-protein. Activity on G (z) -alpha and G (i) - alpha-1 is inhibited by palmitoylation of the G-protein.

Summary: Tissue Location: Expressed in brain and heart. Expressed in brain at protein level. Expressed in prefontal and visual cortex. Isoform 4 and isoform 5 are expressed ubiquitously. Isoform 1, isoform 2 and isoform 3 are not expressed in the cerebellum.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Regulator of G-protein signaling 4, RGP4, RGS4, RGS4