RITA1 Polyclonal Antibody | E-AB-19212

RITA1 Polyclonal Antibody | E-AB-19212 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: C12orf52 , Chromosome 12 open reading frame 52 , RBPJ interacting and tubulin associated 1, RBPJ interacting and tubulin associated protein 1, RBPJ-interacting and tubulin-associated protein, RITA, RITA

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Developmental biology, Neuroscience, Signal transduction, Stem cells

Background: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

Concentration: 1.02 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human RITA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A