RLA-DQ Antibody [2C4] (FITC) | 99-125

RLA-DQ Antibody [2C4] (FITC) | 99-125 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Rabbit

Homology: N/A

Immunogen: Rabbit spleen cells

Research Area: Immunology

Tested Application: E, WB

Application: RLA-DQ Antibody [2C4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

Specificiy: RLA-DQ

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [2C4]

Isotype: IgG2a

Conjugate: FITC

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: N/A

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The monoclonal antibody 2C4 reacts with RLA-DQ-transfected cells, but not with RLA-DR-transfected cells. In normal adult rabbits, the antibody reacts with 30-60% of peripheral blood leukocytes. It has also been reported that the antibody stains lymphocytes and macrophages in the spleen, lymphocytes in the thymic medulla and some cells in the cortex, Kupffer cells in the liver, and synovial lining cells (e.g., infiltrating macrophages) in inflamed synovium. DQalpha transcripts have been detected in bone marrow and spleen and to a lesser extent in appendix, lymph nodes, and other organs.