RNF2 Antibody | 19-735

RNF2 Antibody | 19-735 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human RNF2 (NP_009143.1) .

Research Area: Other

Tested Application: WB, IHC, IF, IP, ChIP

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
IP: 1:50 - 1:200
ChIP: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: Jurkat

Positive Control 3: U-937

Positive Control 4: SH-SY5Y

Positive Control 5: Mouse brain

Positive Control 6: Mouse spleen

Molecular Weight: Observed: 38kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: RNF2, BAP1, DING, BAP-1, HIPI3, RING2, RING1B

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2) . Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2) , an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.