RNF2 Antibody | 28-047

RNF2 Antibody | 28-047 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, Dog, Zebrafish

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF2.

Research Area: Transcription, Cancer

Tested Application: E, WB, IHC

Application: RNF2 antibody can be used for detection of RNF2 by ELISA at 1:312500. RNF2 antibody can be used for detection of RNF2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 29 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein A chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store RNF2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: RNF2, BAP1, DING, BAP-1, HIPI3, RING2, RING1B

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2) . This protein was also found to interact with huntingtin interacting protein 2 (HIP2) , an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.