ROCK2 polyclonal Antibody | BS91176

ROCK2 polyclonal Antibody | BS91176 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC

Application Range: WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200

Background: Rho, the Ras-related small GTPase, is responsible for the regulation of Actin-based cytoskeletal structures, including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been de-scribed, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka) for Rho-associated coil-containing protein kinase. Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: ROCK2 polyclonal Antibody detects endogenous levels of ROCK2 protein.

Molecular Weight: 161 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ROCK-II, ROCK2, KIAA0619, coiled-coil-containing protein kinase 2, KIAA0619, p164 ROCK 2, p164 ROCK-2, Rho associated coiled coil containing protein kinase 2, Rho associated protein kinase 2, Rho associated, coiled coil containing protein kinase II, Rho kinase 2, Rho-associated, Rho-associated protein kinase 2, ROCK 2, Rock II, Rock2, ROCK2, Rock2m, ROK alpha, ROKalpha,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: