ROR1 Polyclonal Antibody | E-AB-13684

ROR1 Polyclonal Antibody | E-AB-13684 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: dJ537F10.1, Inactive tyrosine protein kinase transmembrane receptor ROR1, MGC99659, Neurotrophic tyrosine kinase, Neurotrophic tyrosine kinase receptor related 1, Neurotrophic tyrosine kinase, receptor related 1, NTRKR1, OTTHUMP00000010573, OTTHUMP00000010574, OTTMUSP00000008344, Receptor tyrosine kinase like orphan receptor 1, receptor-related 1, RGD1559469, ROR 1, ROR1, ROR1, RP11 24J23.1, Tyrosine kinase like orphan receptor 1, Tyrosine protein kinase transmembrane receptor ROR1, Tyrosine-protein kinase transmembrane receptor ROR1

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience, Signal Transduction

Background: This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ROR1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A