RPAP3 polyclonal Antibody | BS60239

RPAP3 polyclonal Antibody | BS60239 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. RPAP3 (RNA polymerase II-associated protein 3) is a 665 amino acid protein that contains seven TRP repeats and is expressed as multiple alternatively spliced isoforms. Existing as a tightly associated component of the RNA polymerase II (Pol II) complex, RPAP3 functions to form an interface between Pol II and scaffolding proteins, thereby playing a role in the regulation of protein complex formation.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RPAP3 polyclonal Antibody detects endogenous levels of RPAP3 protein.

Molecular Weight: ~ 76 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RNA polymerase II-associated protein 3

Immunogen: A synthetic peptide corresponding to residues in Human RPAP3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Mitochondrial Control of Apoptosis,