RPL13 Antibody (Center) [APR33453G]

RPL13 Antibody (Center) [APR33453G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This RPL13 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 49-82 amino acids from the Central region of human RPL13.

Cellular Localisation: Cytoplasm.

Molecular Weight: 24261

Clone: Polyclonal

Gene Name: RPL13

Gene ID: 6137

Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:31630789, PubMed:23636399) . The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable) . The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable) . The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable) . As part of the LSU, it is probably required for its formation and the maturation of rRNAs (PubMed:31630789) . Plays a role in bone development (PubMed:31630789) .

Summary: Tissue Location: Higher levels of expression in benign breast lesions than in carcinomas

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: 60S ribosomal protein L13, Breast basic conserved protein 1, RPL13, BBC1