Description
RPRD1A Antibody | 16-279 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 47-276 of human RPRD1A (NP_001290341.1) .
Research Area: Cell Cycle
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: HT-29
Positive Control 2: HeLa
Positive Control 3: A-431
Positive Control 4: Mouse liver
Positive Control 5: Mouse testis
Positive Control 6: Rat brain
Molecular Weight: Observed: 36kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: HsT3101, P15RS, regulation of nuclear pre-mRNA domain-containing protein 1A, CDKN2B-related protein, Cyclin-dependent kinase inhibitor 2B-related protein (p15INK4B-related protein) , cyclin-dependent kinase 2B-inhibitor-related protein, p15INK4B-related protein
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G (1) /S phase progression. This protein also forms homo- and hetrodimers with the protein, regulation of nuclear pre-mRNA domain-containing protein 1B, to form a scaffold that interacts with the C-terminal domain of RNA polymerase II subunit B1 and regulates several aspects of transcription. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 16.