RPS6KA4 Antibody | 13-447

RPS6KA4 Antibody | 13-447 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RPS6KA4 (NP_003933.1) .

Research Area: Apoptosis, Cell Cycle, Immunology, Signal Transduction

Tested Application: WB, IHC, IF

Application: WB: 1:200 - 1:1000
IHC: 1:20 - 1:100
IF: 1:20 - 1:100

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: SH-SY5Y

Positive Control 3: HL-60

Positive Control 4: BT-474

Positive Control 5: Mouse heart

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 115kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Ribosomal protein S6 kinase alpha-4, S6K-alpha-4, 90 kDa ribosomal protein S6 kinase 4, Nuclear mitogen- and stress-activated protein kinase 2, Ribosomal protein kinase B, RSKB, RPS6KA4, MSK2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene.