RPS6KB1 (S6K) monoclonal Antibody | MB64983

RPS6KB1 (S6K) monoclonal Antibody | MB64983 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat, Dog

Application: IF, IHC, WB

Application Range: WB 1:500~2000, IHC 1:150, IF 1:100

Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: ribosomal protein S6 kinase B1

Molecular Weight: 59 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: p70 S6KA; p70 (S6K) -alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A

Immunogen: Full length human recombinant protein of human RPS6KB1 (NP_003152) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A