RREB1 Antibody (C-term) [AMM07668G]

RREB1 Antibody (C-term) [AMM07668G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This RREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1398-1424 amino acids from the C-terminal region of human RREB1.

Cellular Localisation: Nucleus speckle

Molecular Weight: 181420

Clone: Polyclonal

Gene Name: RREB1

Gene ID: 6239

Function: Transcription factor that binds specifically to the RAS- responsive elements (RRE) of gene promoters (PubMed:9305772, PubMed:15067362, PubMed:8816445, PubMed:10390538, PubMed:17550981) . Represses the angiotensinogen gene (PubMed:15067362) . Negatively regulates the transcriptional activity of AR (PubMed:17550981) . Potentiates the transcriptional activity of NEUROD1 (PubMed:12482979) . Promotes brown adipocyte differentiation (By similarity) . May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression (PubMed:8816445) .

Summary: Tissue Location: Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Ras-responsive element-binding protein 1, RREB-1, Finger protein in nuclear bodies, Raf-responsive zinc finger protein LZ321, Zinc finger motif enhancer-binding protein 1, Zep-1, RREB1, FINB