Rrn3 (phospho-S649) polyclonal Antibody | BS4911

Rrn3 (phospho-S649) polyclonal Antibody | BS4911 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1:1000

Background: Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC) . Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Rrn3 (phospho-S649) polyclonal Antibody detects endogenous levels of Rrn3 protein only when phosphorylated at Ser649.

Molecular Weight: ~ 74 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RNA polymerase I-specific transcription initiation factor RRN3; Transcription initiation factor IA; TIF-IA; RRN3; TIFIA

Immunogen: Synthetic phosphopeptide derived from human Rrn3 around the phosphorylation site of Serine 649

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Neuronal and Glial Cell Marker Atlas,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,