RSL1D1 polyclonal Antibody | BS65567

RSL1D1 polyclonal Antibody | BS65567 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse, Rat

Application: WB,IHC-P,

Application Range: WB=1:500-2000 IHC-P=1:400-800 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: RSL1D1, also known as CATX-11, PBK1, L12 or CSIG, is a 490 amino acid nuclear protein that belongs to the ribosomal protein L1P family. Expressed in placenta, RSL1D1 contains many phosphorylated amino acid residues and is encoded by a gene that maps to human chromosome 16p13.13. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RSL1D1 polyclonal Antibody detects endogenous levels of RSL1D1 protein.

Molecular Weight: ~52kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CATX 11; CATX-11; CATX11; Cellular senescence inhibited gene protein; L12; PBK1; CSIG; L12; PBK1; Protein PBK1; Ribosomal L1 domain-containing protein 1; RL1D1_HUMAN; Ribosomal L1 domain containing 1.

Immunogen: KLH conjugated synthetic peptide derived from mouse RSL1D1:311-410/452

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: