RTN3 Polyclonal Antibody | E-AB-66432

RTN3 Polyclonal Antibody | E-AB-66432 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: RTN3, ASYIP, HAP, NSPL2, NSPLII, RTN3-A1

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic peptide of human RTN3 (NP_006045.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 23 kDa/25 kDa/26 kDa/27 kDa/100 kDa/110 kDa/112 kDa

Molecular Weight(Observed): 26 kDa