RTN4RL2 Antibody | 7145

RTN4RL2 Antibody | 7145 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Rat: (100%) , Mouse: (100%)

Immunogen: Rabbit polyclonal RTN4RL2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RTN4RL2.
The immunogen is located within amino acids 330 - 380 of RTN4RL2.

Research Area: Neuroscience

Tested Application: E, WB

Application: RTN4RL2 antibody can be used for detection of RTN4RL2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Specificiy: Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.

Positive Control 1: Cat. No. 1463 - Rat Brain Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 46 kDa

Validation: N/A

Isoform: N/A

Purification: RTN4RL2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: RTN4RL2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: RTN4RL2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: RTN4RL2 Antibody: NgR2, NGRH1, NGRL3, Reticulon-4 receptor-like 2, Nogo receptor-like 3, NgR2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: RTN4RL2 Antibody: Reticulon 4 receptor-like 2 (RTN4RL2) , also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.