rTS Antibody | XW-7885

rTS Antibody | XW-7885 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human

Homology: N/A

Immunogen: 101-250

Research Area: Other

Tested Application: WB

Application: ORF1A antibody can be used for the detection of ORF1A by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 41 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: rTS antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: RTS, TYMSAS, Mitochondrial enolase superfamily member 1, Antisense RNA to thymidylate synthase, rTS, RTS, HSRTSBETA, ORF1A

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: rTS is a gene with convergent and overlapping transcription relative to thymidylate synthase (TS) . rTSβ differs from rTSα by the insertion of an extra 116 nucleotides after base 128 of rTSα and an altered 3'-noncoding region such that rTSβ RNA is not complementary to TS mRNA. rTSα and rTSβ RNAs have open reading frames predicted to encode proteins of 361 and 416 amino acids, respectively. Antibody to rTSβ protein detects two proteins of the predicted molecular weight in the H630 colon tumor cell line. rTSβ is overexpressed 40-70-fold in a 5-fluorouracil-resistant H630 subline compared with 7-8-fold for TS and rTSα