Description
RUNX2 Antibody | 33-058 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: A recombinant protein fragment from the internal region of human RUNX2 was used as the immunogen for this antibody.
Research Area: Cancer, Homeostasis
Tested Application: WB
Application: Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, RUNX2 antibody titration may be required for optimal results.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein A affinity chromatography
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.5 mg/mL
Storage Condition: Aliquot and Store at -20˚C. Avoid freez-thaw cycles.
Alternate Name: RUNX2, CCD, AML3, CCD1, CLCD, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2aA, CBF-alpha-1
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: RUNX (runt-related transcription factor) proteins are a family of transcription factors involved in many different biological systems, including cell differentiation and cancer. RUNX2 is an essential factor in bone development, acting as a scaffold protein for nucleic acids and regulatory factors involved in skeletal gene expression. It is also involved in cancer cell movement, activating factors involved in the metastasis of prostate and breast cancer cells to bone.