S-(5'-Adenosyl)-L-methionine chloride (hydrochloride) | B2826

SAM is a ubiquitous methyl donor. It is a cofactor for methyl transferases such as catechol O-methyltransferase (COMT) and DNA methyltransferase. Most of it is present in the liver, where 85% of all methylation reactions occur. It shows hepatoprotective effects in cultured hepatocytes and mouse models.

SAM is a ubiquitous methyl donor. It is a cofactor for methyl transferases such as catechol O-methyltransferase (COMT) and DNA methyltransferase. Most of it is present in the liver, where 85% of all methylation reactions occur. It shows hepatoprotective effects in cultured hepatocytes and mouse models.

B2826 | S-(5'-Adenosyl)-L-methionine chloride (hydrochloride) DataSheet

Alternate Name/Synonyms: AdoMet SAM, chloride dihydrochloride, S-(5'-Adenosyl)-L-methionine chloride dihydrochloride, (3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4, -dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride dihydrochloride, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine, chloride dihydrochloride, (3-amino-3-carboxypropyl)-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium;chloride;dihydrochloride

Appearance: Lyophilized powder

Formulation:

CAS Number: 86867-01-8

Structure Available?: True

Peptide sequence:

Salt Form: False

Molecular Formula: C₁₅H₂₅Cl₃N₆O₅S

Molecular Weight: 507.82

Cell-Permeable?: True

Purity: ≥95%

Solubilities: 1 mg/ml in methanol in 0, 5 mg/ml in in Water

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A methyl donor and a cofactor for catechol O-methyltransferase (COMT) and DNA methyltransferase

MDL Number:

PubChem CID: 118821583

SMILES: C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O.Cl.Cl.[Cl-]

InChi: InChI=1S/C15H22N6O5S.3ClH/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;;;/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);3*1H/t7?,8-,10-,11-,14-,27?;;;/m1.../s1

InChi Key: KBAFOJZCBYWKPU-SPWYAPBOSA-N