S107 free base | B3354

S107 free base | B3354

Description: S107 is a Type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. The intracellular Ca2+ leak was significantly reduced in mice treated with S107.

Alternate Name/Synonyms: S-107 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

Appearance: Solid

Formulation:

CAS Number: 927871-76-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₁₅NOS

Molecular Weight: 209.31

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Tag Line: A Type 1 ryanodine receptor (RyR1) stabilizer

MDL Number:

PubChem CID: 24763624

PubCnk: https://pubchem.ncbi.nlm.nih.gov/compound/24763624

SMILES: CN1CCSC2=C(C1)C=C(C=C2)OC

InChi: InChI=1S/C11H15NOS/c1-12-5-6-14-11-4-3-10(13-2)7-9(11)8-12/h3-4,7H,5-6,8H2,1-2H3

InChi Key: BGVCEGVSQDOGSB-UHFFFAOYSA-N

Category: Biochemicals