Salvinorin B | B1923

Salvinorn B is a potent and selective κ-opioid DREADD (KORD) agonist (EC₅₀ = 11.8 nM). DREADDs are chemogenetic tools widely used to remotely control cellular signaling, neuronal activity, and behavior. Displays no analgesic or ataxic effects in wild type mice.

Salvinorn B is a potent and selective κ-opioid DREADD (KORD) agonist (EC₅₀ = 11.8 nM). DREADDs are chemogenetic tools widely used to remotely control cellular signaling, neuronal activity, and behavior. Displays no analgesic or ataxic effects in wild type mice.

B1923 | Salvinorin B DataSheet

Alternate Name/Synonyms: (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-Furanyl)dodecahydro-9-hydroxy-6a,10b-dimethyl-4,10-dioxo 2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester, Divinorin B

Appearance: White solid

Formulation: N/A

CAS Number: 92545-30-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₆O₇

Molecular Weight: 390.43

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (~ 5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective κ-opioid DREADD (KORD) agonist

MDL Number: MFCD16036232

PubChem CID: 11440685

SMILES: CC12CCC3C(=O)OC(CC3(C1C(=O)C(CC2C(=O)OC)O)C)C4=COC=C4

InChi: InChI=1S/C21H26O7/c1-20-6-4-12-19(25)28-15(11-5-7-27-10-11)9-21(12,2)17(20)16(23)14(22)8-13(20)18(24)26-3/h5,7,10,12-15,17,22H,4,6,8-9H2,1-3H3/t12-,13-,14-,15-,17-,20-,21-/m0/s1

InChi Key: BLTMVAIOAAGYAR-CEFSSPBYSA-N