Saporin | AS13 2688

Saporin | AS13 2688 | Gentaur UK, US & Europe Distribution

Immunogen: Saporin, whole molecule

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Serum

Format: Lyophilized

Tested Application: ELISA (ELISA), Immunihistochemistry (IHC), Immunofluorescence (IF), Western blot (WB)

Related Products: N/A

Recommended Dilutions: 1 : 200-1 : 2000 is recommended, Optimal dilutions/concentrations should be determined by the end user

Molecular weight: 29, 5 kDa

Confirmed Reactivity: Purified saporin

Predicted Reactivity: N/A

Not reactive in: N/A

Additional Information: N/A

Background: Saporin is a ribosome-inactivating protein (RIP) of type I. This monomeric RNA N-glycosidase purified from seeds of the plant Saponaria officinalis also known as Soapwort, is capable of specific depurination of eukaryotic ribosomes thus arresting protein synthesis. No ligand has been identified in saporin hence its inability to transverse the cell membrane. Due to its toxicity and stability of the structure, saporin has proven extremely useful for construction of immunotoxins.

Reconstitution: For reconstitution add 100 µl of sterile water

Storage: For long term stability requires storage. preferably in small aliquots at -20ºC or lower. It is recommended that a thawed sample is stored at 4ºC for no longer than 2 weeks. Allocation of appropriate anti-bacterial agent can increase shelf life by several weeks. Diluted serum should be prepared as required. Glycerol (1:1) can be added to neat serum for additional stability if intended use does not prevent this

TAIR Nnumbre: N/A

Category: Cancer

Research Area: Cancer Research