SAR1B Antibody (Center) [AMM07712G]

SAR1B Antibody (Center) [AMM07712G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.

Cellular Localisation: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9QVY3}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9QVY3}. Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q9QVY3}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9QVY3}. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region. {ECO:0000250|UniProtKB:Q9QVY3}

Molecular Weight: 22410

Clone: Polyclonal

Gene Name: SAR1B {ECO:0000303|PubMed:33186557, ECO:0000312|HGNC:HGNC:10535}

Gene ID: 51128

Function: GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity) . Activated by the guanine nucleotide exchange factor PREB (By similarity) . Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity) . Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis (PubMed:33186557) .

Summary: Tissue Location: Expressed in many tissues including small intestine, liver, muscle and brain.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB, FC

Dilution: IHC-P--1:100~500 WB--1:1000 FC--1:10~50

Synonyms: GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB