SARS-COV-2 Nucleocapsid Protein Antibody [3E8A5] | 24-036

SARS-COV-2 Nucleocapsid Protein Antibody [3E8A5] | 24-036 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Virus

Homology: N/A

Immunogen: E.coli derived SARS-COV-2 Nucleoproteins Ser2-Ala419���Gly335Ala) Accession #QHD43423.2

Research Area: Infectious Disease, COVID-19

Tested Application: E

Application: SARS-COV-2 Nucleocapsid Sandwich Elisa:

ELISA Capture: Recommended Concentration:0.5-2ug/mL, Sample: SARS-CoV-2 Nucleocapsid Protein Antibody���CAP)

ELISA Capture: Recommended Concentration:0.005-0.02ug/mL, Sample: SARS-CoV-2 Nucleocapsid Protein Antibody

Standard:Recommended Concentration: 7.8-500pg/mL, Sample: Recombinant SARS-COV-2 Nucleocapsid Protein with His tag

Specificiy: SARS-COV-2

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Affinity purification

< 1.0 EU/ug of the protein by LAL method.

Clonality: Recombinant Monoclonal

Clone: 3E8A5

Isotype: Rabbit IgG

Conjugate: Unconjugated

Physical State: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered solution in PBS, pH7.4

Concentration: 1 mg/ml

Storage Condition: 2˚C - 8˚C for one month, -20˚C to -80˚C for one year. Avoid repeated freeze-thaw cycles

Alternate Name: SARS-CoV-2 Nucleocapsid Protein, SARS-CoV-2 NP, nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2], novel coronavirus N Protein, novel coronavirus Nucleocapsid Protein, 2019-nCoV Nucleoprotein, 2019-nCoV N, 2019nCoV N, 2019-nCoV N Protein, 2019 peak N Protein, 2019-nCoV nucleocapsid protein.

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.