SARS virus EnvE Antibody (C-term) [APR32227G]

SARS virus EnvE Antibody (C-term) [APR32227G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: S

Specificity: This SARS virus EnvE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47~76 amino acids from the C-terminus region of SARS EnvE protein.

Cellular Localisation: Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus membrane {ECO:0000255|HAMAP-Rule:MF_04204, ECO:0000269|PubMed:21450821, ECO:0000269|PubMed:24788150}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04204}. Note=Colocalizes with S in the host endoplasmic reticulum-Golgi intermediate compartment (PubMed:20861307) The cytoplasmic tail functions as a Golgi complex-targeting signal {ECO:0000255|HAMAP-Rule:MF_04204, ECO:0000269|PubMed:20861307, ECO:0000269|PubMed:21450821}

Molecular Weight: 8361

Clone: Polyclonal

Gene Name: E {ECO:0000255|HAMAP-Rule:MF_04204}

Gene ID: 1489671

Function: Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis (By similarity) . Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: N/A

Dilution: N/A

Synonyms: Envelope small membrane protein, E protein, sM protein, E, sM