SASH1 Polyclonal Antibody | E-AB-53327

SASH1 Polyclonal Antibody | E-AB-53327 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 2500002E12Rik, dJ323M4, dJ323M4.1, KIAA0790, PEPE 1, PEPE1, Proline glutamate repeat containing protein, Proline-glutamate repeat-containing protein, RP3 323M4.1, SAM and SH3 domain containing 1, SAM and SH3 domain containing protein 1, SAM and SH3 domain-containing protein 1, SASH 1, Sash1, SASH1

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer

Background: This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients.

Concentration: 0.78 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human SASH1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 137 kDa

Molecular Weight(Observed): Refer to figures