Saxagliptin | 9528

Saxagliptin is hydroxyadamantyl compound that acts as a potent, selective and reversible dipeptidyl peptidase-4 (DPP-4) inhibitor (IC₅₀ = 26 nM). An anti-diabetic agent.

Saxagliptin is hydroxyadamantyl compound that acts as a potent, selective and reversible dipeptidyl peptidase-4 (DPP-4) inhibitor (IC₅₀ = 26 nM). An anti-diabetic agent.

9528 | Saxagliptin DataSheet

Alternate Name/Synonyms: (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile; BMS-477118; Onglyza

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 361442-04-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₂₅N₃O₂

Molecular Weight: 315.41

Cell-Permeable?: Yes

Purity: ≥97% by HPLC

Solubilities: DMSO (>40 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A dipeptidyl peptidase-4 (DPP-4) inhibitors set

MDL Number: N/A

PubChem CID: 11243969

SMILES: C1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)CC(C5)(C4)O)N

InChi: InChI=1S/C18H25N3O2/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17/h10-15,23H,1-7,9,20H2/t10?,11?,12-,13+,14+,15-,17?,18?/m1/s1

InChi Key: QGJUIPDUBHWZPV-SGTAVMJGSA-N