SB-742457 | 9568

SB-742457 is a highly selective 5-HT6 receptor antagonist with potential cognition, memory and learning-enhancing effects; displays >100-fold selectivity over other receptors. in anxiolytic and antidepressant-like activity. SB-742457 shows increasing pro-cognitive effects in patients with Alzheimer’s Disease (AD).

SB-742457 is a highly selective 5-HT6 receptor antagonist with potential cognition, memory and learning-enhancing effects; displays >100-fold selectivity over other receptors. in anxiolytic and antidepressant-like activity. SB-742457 shows increasing pro-cognitive effects in patients with Alzheimer’s Disease (AD).

9568 | SB-742457 DataSheet

Alternate Name/Synonyms: 3-(Benzenesulfonyl)-8-piperazin-1-ylquinoline; RVT-101

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 607742-69-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₁₉N₃O₂S

Molecular Weight: 353.44

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>40 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A highly selective 5-HT6 receptor antagonist

MDL Number: N/A

PubChem CID: 11256720

SMILES: C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4

InChi: InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2

InChi Key: JJZFWROHYSMCMU-UHFFFAOYSA-N