SCF polyclonal Antibody | BS91210

SCF polyclonal Antibody | BS91210 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC/IF IHC FC

Application Range: WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:100-1:500 FC:1:50-1:100

Background: Stem cell factor (SCF) is the ligand for the transmembrane tyrosine kinase receptor proto-oncogene c-Kit. SCF, also designated KL, MGF and SLF, is a pleiotropic cytokine that has two alternatively spliced forms, 248 and 220 amino acids in length in human and mouse systems, respectively. Both the larger form and the smaller form are cleaved to produce soluble forms. The smaller splice variant lacks the proteolytic cleavage site, between amino acids 149 and 177 of the larger SCF form. The larger form of SCF is expressed in fibroblasts, brain and thymus, while the smaller form is found in spleen, testis, placenta and cerebellum. The SCF ligand is essential for the development of germ cells, hematopoietic progenitor cells and melanocyte precursors. SCF can stimulate the proliferation of mature mast cells as well as the maturation and proliferation of immature mast cells.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: SCF polyclonal Antibody detects endogenous levels of SCF protein.

Molecular Weight: 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MGF, SCF, sKITLG, KITLG, C kit ligand, C-kit ligand, Ckit ligand, DCUA, DFNA69, DKFZp686F2250, familial progressive hyperpigmentation 2, FPH2, FPHH, KIT ligand, Kitl, KITLG, KL 1, KL1, Mast cell growth factor, MGF, MGF stem cell factor, SCF, SCF, SF, SHEP7, sKITLG, Soluble KIT ligand, Steel factor, steel, mouse, homolog of, Stem cell factor, Stem cell factor precursor,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: