SDF-1α/CXCL2, rat recombinant | 7199

SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1α is a 7.9 kDa protein containing 68 amino acid residues.

7199 | SDF-1α/CXCL2, rat recombinant DataSheet

Biomolecule/Target :CXCL2

Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF

Alternates names: Stromal-Cell Derived Factor-1, CXCL12, PBSF

Taglines: Chemoattracts B and T cells and induces migration of CD34+ stem cells

NCBI Gene ID #: 24772

NCBI Gene Symbol: SDF-1

Gene Source: RAT

Accession #: Q9QZD1

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGE: ≥98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/ug of protein (<1EU/ug).

Activity (Specifications/test method): Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml.

Biological activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 7.9 kDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans