SDF-1beta Antibody | 5393

SDF-1? (stromal cell-derived factor-?), also known as pre-B-cell growth-stimulating factor (PBSF), is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.

5393 | SDF-1beta Antibody DataSheet

Antibody Target: SDF-1b

Target Alternative Name: SDF-1b, SDF 1b, SDF 1beta, SDF 1 beta, SDF -1, SDF, Stromal cell-derived factor 1;DF-1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor; PBSF;SDF-1-beta

Tag Line:

Category: SDF

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Mouse, rat

Immunogen Sequence: E. coli-expressed mouse SDF-1?

Accession #: P40224

Gene ID: 20315

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% Proclin.

Purification: Affinity purified

Application: Western blot, Immunoprecipitation, Immunohistochemistry

Positive Control:

Application And Usages: Western blot analysis (0.5-4 µg/ml). Per researcher’s feedback, the antibody can be used in immunoprecipitation (4-8 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually. Cross-reactivity to SDF-1? of other species has not been determined.

Country of Animal Origin: China

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified: Not Verified

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified