SEMA6A Antibody (C-term) [APR13253G]

SEMA6A Antibody (C-term) [APR13253G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SEMA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 998-1028 amino acids from the C-terminal region of human SEMA6A.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein

Molecular Weight: 114395

Clone: Polyclonal

Gene Name: SEMA6A

Gene ID: 57556

Function: Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Semaphorin-6A, Semaphorin VIA, Sema VIA, Semaphorin-6A-1, SEMA6A-1, SEMA6A, KIAA1368, SEMAQ