SERBP1 Antibody (Center) [APR04693G]

SERBP1 Antibody (Center) [APR04693G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M, Rat

Specificity: This SERBP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-183 amino acids from the Central region of human SERBP1.

Cellular Localisation: Cytoplasm. Nucleus. Cytoplasm, perinuclear region

Molecular Weight: 44965

Clone: Polyclonal

Gene Name: SERBP1 (HGNC:17860)

Gene ID: 26135

Function: May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation (PubMed:28695742) .

Summary: Tissue Location: Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Plasminogen activator inhibitor 1 RNA-binding protein, PAI1 RNA-binding protein 1, PAI-RBP1, SERPINE1 mRNA-binding protein 1, SERBP1, PAIRBP1