SERPINB8 Polyclonal Antibody | E-AB-15386

SERPINB8 Polyclonal Antibody | E-AB-15386 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CAP 2, CAP-2, CAP2, Cytoplasmic antiproteinase 2, OTTHUMP00000067000, OTTHUMP00000067001, Peptidase inhibitor 8, PI 8, PI-8, PI8, Protease inhibitor 8 (ovalbumin type), Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 8, Serpin B8, Serpin peptidase inhibitor clade B (ovalbumin) member 8, Serpinb8, SPB8

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Cardiovascular

Background: The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human SERPINB8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:30-1:150

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A