SERPINC1 polyclonal Antibody | BS91226

SERPINC1 polyclonal Antibody | BS91226 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:500-1;1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Antithrombin III (ATIII), an extracellular plasma protein, is a crucial serine protease inhibitor that regulates the coagulation cascade in blood. The inhibitory activity of ATIII is amplified in the presence of heparin. ATIII inhibits Thrombin and Factors IXa, Xa and XIa. Defects in the gene SERPINC1, which encodes for ATIII, can cause ATIII deficiency, an autosomal dominant disease which is a risk factor for hereditary thrombophilia.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: SERPINC1 polyclonal Antibody detects endogenous levels of SERPINC1 protein.

Molecular Weight: 53 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ATIII, SERPINC1, AT3, ANT3, Antithrombin, Antithrombin III, Antithrombin-III, AntithrombinIII, AT 3, AT III, AT3, AT3D, ATIII, Heparin cofactor I, MGC22579, Serine (or cysteine) proteinase inhibitor clade C (antithrombin) member 1, Serine cysteine proteinase inhibitor clade C member 1, Serine proteinase inhibitor clade C member 1, Serpin C1, Serpin family C member 1, Serpin peptidase inhibitor clade C (antithrombin) member 1, SERPINC1, THPH7,

Immunogen: Recombinant protein within human SERPINC1 aa 150-400.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: