SERPINI1 Antibody (N-term) [APR13292G]

SERPINI1 Antibody (N-term) [APR13292G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SERPINI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human SERPINI1.

Cellular Localisation: Secreted. Cytoplasmic vesicle, secretory vesicle lumen. Perikaryon

Molecular Weight: 46427

Clone: Polyclonal

Gene Name: SERPINI1

Gene ID: 5274

Function: Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin (PubMed:9442076, PubMed:26329378, PubMed:19265707, PubMed:19285087, PubMed:11880376) . May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable) .

Summary: Tissue Location: Detected in brain cortex and hippocampus pyramidal neurons (at protein level) (PubMed:17040209) . Predominantly expressed in the brain (PubMed:9070919) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, IF, FC, WB

Dilution: WB--1:1000 IHC-P--1:100~500 IF--1:10~50 FC--1:10~50

Synonyms: Neuroserpin, Peptidase inhibitor 12, PI-12, Serpin I1, SERPINI1, PI12