SFRS15 (V641) polyclonal Antibody | BS3953

SFRS15 (V641) polyclonal Antibody | BS3953 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SFRS15 (V641) polyclonal Antibody detects endogenous levels of SFRS15 protein.

Molecular Weight: ~ 126 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Splicing factor, arginine/serine-rich 15; CTD-binding SR-like protein RA4; SR-related and CTD-associated factor 4; SCAF4; KIAA1172; SFRS15

Immunogen: Synthetic peptide, corresponding to amino acids 611-660 of Human SFRS15.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: