SFXN3 Antibody (C-term) [APR10922G]

SFXN3 Antibody (C-term) [APR10922G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SFXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-314 amino acids from the C-terminal region of human SFXN3.

Cellular Localisation: Mitochondrion membrane {ECO:0000269|PubMed:30442778, ECO:0000269|Ref.4}; Multi-pass membrane protein

Molecular Weight: 35503

Clone: Polyclonal

Gene Name: SFXN3 {ECO:0000303|PubMed:30442778, ECO:0000312|HGNC:HGNC:16087}

Gene ID: 81855

Function: Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778) . Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Sideroflexin-3, SFXN3