SGC-CBP30 | 9554

SGC-CBP30 is a potent and selective CREBBP/EP300 bromodomain inhibitor with IC values of 21-69 and 38 nM for CREBBP and EP300 bromodomains, respectively. SGC-CBP30 has little activity against other bromodomains at concentrations up to 1 mM.

SGC-CBP30 is a potent and selective CREBBP/EP300 bromodomain inhibitor with IC values of 21-69 and 38 nM for CREBBP and EP300 bromodomains, respectively. SGC-CBP30 has little activity against other bromodomains at concentrations up to 1 mM.

9554 | SGC-CBP30 DataSheet

Alternate Name/Synonyms: 2-[2-(3-Chloro-4-methoxyphenyl)ethyl]-5-(dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-1,3-benzodiazole

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1613695-14-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₃₃ClN₄O₃

Molecular Weight: 509.04

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: a potent and selective CREBBP/EP300 bromodomain inhibitor

MDL Number: N/A

PubChem CID: 72201027

SMILES: CC1=C(C(=NO1)C)C2=CC3=C(C=C2)N(C(=N3)CCC4=CC(=C(C=C4)OC)Cl)CC(C)N5CCOCC5

InChi: InChI=1S/C28H33ClN4O3/c1-18(32-11-13-35-14-12-32)17-33-25-8-7-22(28-19(2)31-36-20(28)3)16-24(25)30-27(33)10-6-21-5-9-26(34-4)23(29)15-21/h5,7-9,15-16,18H,6,10-14,17H2,1-4H3/t18-/m0/s1

InChi Key: GEPYBHCJBORHCE-SFHVURJKSA-N