763

SGCE Polyclonal Antibody | E-AB-60902

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SKU:
763-E-AB-60902-GEN
NULL307.00 - NULL593.00

Description

SGCE Polyclonal Antibody | E-AB-60902 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: SGCE, DYT11, ESG, epsilon-SG

Application: WB, IHC, IF

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Developmental Biology, Signal Transduction

Background: This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human SGCE (NP_003910.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 49 kDa/51 kDa/52 kDa

Molecular Weight(Observed): 55 kDa

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