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SGI-1776 | 2554
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SGI-1776 is a potent and ATP-competitive Pim kinase inhibitor (IC₅₀’s = 7, 363, and 69 nM for Pim-1, Pim-2 and Pim-3, respectively). SGI-1776 also inhibits FLT3 (IC₅₀ = 44 nM). Induces apoptosis in...
26-2554-GEN
SGI-1027 | 2726
26
SGI-1027 is a selective DNA methyltransferase (DNMT) inhibitor. Inhibits DNMT1, DNMT3A, and DNMT3B with IC₅₀ values of 6, 8, and 7.5 µM, respectively. Treatment of different cancer cell lines with...
26-2726-GEN
SGI-7079 | B1202
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SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 significantly inhibits the proliferation of SUM149 or KPL-4 cells with an IC₅₀ of 0.43 or 0.16 μM,...
26-B1202-GEN
17-DMAG hydrochloride | 1776
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A water-soluble analog of 17-AAG (Cat. No. 1774-1,5) that displays better stability and low in vivo toxicity similar to 17-AAG, but undergoes limited metabolism compared to 17-AAG. Binds specifically...
26-1776-GEN
AKR1C1 antibody | 10R-1776
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AKR1C1 antibody | 10R-1776 | Activity Code: ACTIVE Product Type: Primary Antibodies Product Subtype: Monoclonal Antibodies Research Area: Cardiac Markers Short Description: Mouse...
118-10R-1776-GEN