SGSM2 Antibody | 7035

SGSM2 Antibody | 7035 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: SGSM2 antibody was raised against an 18 amino acid synthetic peptide near the center of human SGSM2.
The immunogen is located within amino acids 650 - 700 of SGSM2.

Research Area: Neuroscience

Tested Application: E, WB, IF

Application: SGSM2 antibody can be used for detection of SGSM2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: Multiple isoforms of SGSM2 are known to exist. SGSM2 antibody is predicted to not cross react with other SGSM family proteins.

Positive Control 1: Cat. No. 1362 - Human Cerebellum Tissue Lysate

Positive Control 2: Cat. No. 10-301 - Human Brain Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 116 kDa

Validation: N/A

Isoform: N/A

Purification: SGSM2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SGSM2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SGSM2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: SGSM2 Antibody: RUTBC1, KIAA0397, RUTBC1, Small G protein signaling modulator 2, RUN and TBC1 domain-containing protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SGSM2 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.