SH3BP2 Antibody | 27-092

SH3BP2 Antibody | 27-092 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SH3BP2.

Research Area: Cancer, Signal Transduction, Immunology

Tested Application: E, WB

Application: SH3BP2 antibody can be used for detection of SH3BP2 by ELISA at 1:1562500. SH3BP2 antibody can be used for detection of SH3BP2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: 721_B Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 62 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by peptide affinity chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store SH3BP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: SH3BP2, 3BP2, CRBM, CRPM, FLJ42079, RES4-23, 3BP-2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK) , and basophilic cells. Mutations in this gene result in cherubism.