SH3GL1 Antibody | XW-8087

SH3GL1 Antibody | XW-8087 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: 1-360

Research Area: Neuroscience, Signal Transduction

Tested Application: WB

Application: SH3-containing Grb-2-like 1 protein antibody can be used for the detection of SH3-containing Grb-2-like 1 protein by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 39.8 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: SH3GL1 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: CNSA1, SH3D2B, Endophilin-A2, EEN fusion partner of MLL, EEN, CNSA1, SH3P8, SH3containing Grb2like 1 protein

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SH3GL1 may play a regulatory role in synaptic vesicle recycling. It interacts with SYNJ1 and DNM1 through its SH3 domain with the proline-rich region of mixed lineage Leukemia (MLL) in either the fusion or the normal MLL protein. This protein is located in cytoplasmic, and peripheral membrane protein associated with internal membranes. Concentrated in presynaptic nerve terminals in neurons (By similarity) . It���s expressed ubiquitously. Higher expression in pancreas, placenta, prostate, testis and uterus. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.