SH3KBP1 Antibody | 18-411

SH3KBP1 Antibody | 18-411 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 136-271 of human SH3KBP1 (NP_114098.1) .

Research Area: Apoptosis, Cancer, Cell Cycle, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: THP-1

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 73kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: AGMX2, CD2BP3, CIN85, GIG1HSB-1, HSB1, IMD61, MIG18, SH3 domain-containing kinase-binding protein 1, CD2-binding protein 3, SH3-domain kinase binding protein 1, Src family kinase-binding protein 1, c-Cbl-interacting protein, cbl-interacting protein of 85 kDa, human Src family kinase-binding protein 1, migration-inducing gene 18, src-related kinase binding protein-1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.