Description
A synthetic analog of Lovastatin (Cat. No. 1692-50, 250). Cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase. Inhibits the biosynthesis of isoprenoids and prevents small G protein activation.
Simvastatin is a synthetic analog of Lovastatin (Cat. No. 1692-50, 250). Cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase. Inhibits the biosynthesis of isoprenoids and prevents small G protein activation.
Alternate Name/Synonyms: MK-733; Synvinolin
Appearance: White solid
Formulation: N/A
CAS Number: 79902-63-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₅H₃₈O₅
Molecular Weight: 418.57
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (25 mg/ml) or Ethanol (30 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A HMG-CoA inhibitor
MDL Number: MFCD00072007
PubChem CID: 54454
SMILES: CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
InChi: InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChi Key: RYMZZMVNJRMUDD-HGQWONQESA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |