SIN3B polyclonal Antibody | BS5930

SIN3B polyclonal Antibody | BS5930 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IF

Application Range: WB: 1:500~1:1000 IF: 1:50~1:200

Background: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SIN3B polyclonal Antibody detects endogenous levels of SIN3B protein.

Molecular Weight: ~ 40, 129, 133 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b; KIAA0700

Immunogen: Synthetic peptide, corresponding to amino acids 260-305 of Human SIN3B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: