SL327 | B1694

SL-327 is a selective inhibitor of MEK1 and MEK2 with IC50 value of 0.18 and 0.22 μM, respectively.

SL-327 is a selective inhibitor of MEK1 and MEK2 with IC50 value of 0.18 and 0.22 μM, respectively.

B1694 | SL327 DataSheet

Alternate Name/Synonyms: SL327; SL-327; SL 327; α-[amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)-benzeneacetonitrile; (Z)-3-amino-3-(4-aminophenyl)sulfanyl-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile

Appearance: Solid

Formulation: N/A

CAS Number: 305350-87-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₂F₃N₃S

Molecular Weight: 335.4

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective inhibitor of MEK1 and MEK2

MDL Number: MFCD06411432

PubChem CID: 9549284

SMILES: C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F

InChi: InChI=1S/C16H12F3N3S/c17-16(18,19)14-4-2-1-3-12(14)13(9-20)15(22)23-11-7-5-10(21)6-8-11/h1-8H,21-22H2/b15-13+

InChi Key: JLOXTZFYJNCPIS-FYWRMAATSA-N