SLAMF4 Antibody | 6253

SLAMF4 Antibody | 6253 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: SLAMF4 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human SLAMF4.
The immunogen is located within the last 50 amino acids of SLAMF4.

Research Area: Immunology

Tested Application: E, WB, IF

Application: SLAMF4 antibody can be used for detection of SLAMF4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: At least three isoforms of SLAMF4 are known to exist. SLAMF4 antibody is predicted to not cross-react with other SLAM protein family members.

Positive Control 1: Cat. No. 1224 - Daudi Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: SLAMF4 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SLAMF4 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SLAMF4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: SLAMF4 Antibody: 2B4, NAIL, Nmrk, NKR2B4, SLAMF4, 2B4, Natural killer cell receptor 2B4, NK cell activation-inducing ligand

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SLAMF4 Antibody: The signaling lymphocyte-activation molecule family member 4 (SLAMF4) , also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.